Showing results for inauthor:Bernhard T. Baune of about 25 books (Page 1) ordered by Relevancy
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Description: Abstract: Background The serotonin transporter gene (SLC6A4; 5-HTT; SERT) is considered a prime candidate in pharmacogenetic research in major depressive disorder (MDD). Besides genetic variation, recent advances have spotlighted the involvement of epigenetic mechanisms such as DNA methylation in predicting antidepressant treatment response in "pharmaco-epigenetic" approaches. In MDD, lower SLC6A4...
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Description: Major Depressive Disorder (MDD) is a clinically and neurobiologically highly heterogenous mood disorder that consists of a variety of symptom clusters including mood symptoms, physical symptoms, and cognitive symptoms. While the traditional model of depression implicates mood as the primary symptom cluster, a more recently published conceptual understanding of depression has extended to also inclu...
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